SQTSpicules 发表于 2026-9-14 15:46

Efficient Transdermal Delivery via Hollow Sponge Spicules

A breakthrough study published at Xiamen University in Bioengineering & Translational Medicine verifies that hollow sponge spicules serve as an advanced microneedle platform for high-efficiency transdermal delivery of proteins, antibodies, nucleic acids and other biomacromolecules. With a skin penetration rate of 7.69%, the innovative structure surpasses traditional microneedles and iontophoresis technologies, offering a promising solution to break through human skin barriers for topical active ingredients.

The academic achievement strongly validates the commercial value of hydrolyzed sponge (sponge spicule), a natural marine biomaterial widely applied in premium skincare and aesthetic products. Featuring inherent micro-needle structures, natural sponge spicules create temporary microchannels on the stratum corneum to assist deep skin absorption. The newly explored hollow structure further upgrades the material’s loading and delivery capacity, effectively solving the core industry pain point of poor permeability of large-molecule skincare actives.

Translating cutting-edge laboratory technology into industrial-grade commercial products, Hunan Sunshine Bio-Tech leads the mass production and standardized application of high-purity hydrolyzed sponge raw materials. After years of technical polishing, the company has mastered mature processes including precise purification, enzymatic hydrolysis and impurity removal of natural sponges. It stably supplies hydrolyzed sponge with a spicule purity of 99.9% and stable morphological structure, fully compliant with global cosmetic ingredient safety standards.

Different from unstable lab samples, Hunan Sunshine Bio-Tech’s hydrolyzed sponge adopts GMP-aligned production standards, with strict microbial control and multi-batch stability testing. The company supports global bulk orders, small-batch trial customization and formula debugging services, covering FOB and DAP international shipping modes. The industrialized sponge spicule materials efficiently boost the transdermal absorption of collagen, peptides, PDRN and other macromolecular actives, empowering finished skincare products with more tangible and stable efficacy.

Xiamen University’s frontier research lays a solid theoretical foundation for the transdermal delivery application of sponge spicules, while Hunan Sunshine Bio realizes the industrial landing and global popularization of this marine biomaterial. The integration of academic research and industrial production continuously drives technological innovation in functional skincare and non-invasive aesthetic fields.

Core Applications
Functional Skincare: Enhance transdermal penetration of peptides, hyaluronic acid, collagen and other macromolecular actives
Professional Aesthetics: Gentle physical skin resurfacing, non-invasive skin barrier opening and absorption boosting
Advanced R&D: Formula development for biomacromolecule transdermal delivery systems
Hunan sunshine Bio-Tech Co.,ltd
Changsha RongqQing Trading Co.,ltd
Address: Building E7, Lugu Enterprise Plaza, Lugu Street, Yuelu District, Changsha City, Hunan Province
Email: [email protected]
Website: www.sunshineextract.com
https://sunsqt.en.alibaba.com
Tel/Wechat/Whatsapp: +861550749062
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